Protein Info for IAI46_15950 in Serratia liquefaciens MT49

Annotation: flagellar hook assembly protein FlgD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 225 PF03963: FlgD" amino acids 6 to 75 (70 residues), 78.1 bits, see alignment E=6.8e-26 PF13861: FLgD_tudor" amino acids 84 to 222 (139 residues), 46.3 bits, see alignment E=6.2e-16 PF13860: FlgD_ig" amino acids 114 to 181 (68 residues), 79.6 bits, see alignment E=2.1e-26

Best Hits

Swiss-Prot: 64% identical to FLGD_ECOLI: Basal-body rod modification protein FlgD (flgD) from Escherichia coli (strain K12)

KEGG orthology group: K02389, flagellar basal-body rod modification protein FlgD (inferred from 96% identity to spe:Spro_2968)

Predicted SEED Role

"Flagellar basal-body rod modification protein FlgD" in subsystem Flagellar motility or Flagellum

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (225 amino acids)

>IAI46_15950 flagellar hook assembly protein FlgD (Serratia liquefaciens MT49)
MAIAATTTESLDNSVIGANAKNNTSQDLSNSFLTLLVAQLKNQDPTNPMQNNELTSQLAQ
INTVQGIEKLNTTLGSISGQINSNQSLQATALIGHGVMVPGSNILAGSKDGKVSTTPFGL
ELERAADSVTATITDATGKAVRTIDLGGLTAGVHSFSWDGSMTDGTTAPDGAYSFTINAK
ANGEQLVARNLHFGMVNGVIRDANGAKLDLGLAGSATLEDVRQIL