Protein Info for IAI46_14910 in Serratia liquefaciens MT49

Annotation: helix-turn-helix domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 128 PF12833: HTH_18" amino acids 30 to 108 (79 residues), 79 bits, see alignment E=2.7e-26 PF00165: HTH_AraC" amino acids 69 to 108 (40 residues), 34.7 bits, see alignment E=1.5e-12

Best Hits

Swiss-Prot: 41% identical to SOXS_SALTY: Regulatory protein SoxS (soxS) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: None (inferred from 98% identity to spe:Spro_2833)

Predicted SEED Role

"Regulatory protein soxS"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (128 amino acids)

>IAI46_14910 helix-turn-helix domain-containing protein (Serratia liquefaciens MT49)
MIQEHHLSLVCALSKWVETHLGRVIHLEELAEYSGYSLWHMQKLFKEATGISLGKYIRER
RLAGAVYQLRTSDASIFDIALDFGFGSQSHFTYMFRKRFNITPYDFRQDLSVDLHIAPPL
HVIHQKTA