Protein Info for IAI46_14855 in Serratia liquefaciens MT49

Annotation: MBL fold metallo-hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 332 PF13483: Lactamase_B_3" amino acids 73 to 285 (213 residues), 79.5 bits, see alignment E=4.3e-26 PF00753: Lactamase_B" amino acids 75 to 238 (164 residues), 31 bits, see alignment E=3.7e-11 PF12706: Lactamase_B_2" amino acids 88 to 286 (199 residues), 155.6 bits, see alignment E=2e-49

Best Hits

KEGG orthology group: None (inferred from 92% identity to spe:Spro_2823)

Predicted SEED Role

"FIG01055989: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (332 amino acids)

>IAI46_14855 MBL fold metallo-hydrolase (Serratia liquefaciens MT49)
MKITNRYYDAGKAHHTPQGFRNPEPTLRREGDLKRWQDERKQQGLPKPPQMGYQQFTQRW
WQQADLSGSDNGIWWLGHASMLLRLEGRYILIDPVLSQRASPLSFYGPKRKTPTPLTVQQ
LPMVDVVLISHNHYDHLDRRTIRQLARRFPHATFIVPLGLKSWFRRYRLQRVEELDWWDS
LQLGDLTFHSTPARHWSMRTLWDRNRSLWCGWVIHHPALRFYFSGDSGYSERLADIGARL
GPFDVAALPIGAYAPRWFMQEQHMDPQQSVTLYQQLNAPQVIPIHWGVFELADESLDEPP
QQLKLALSSAGIEQHRFRPIKIGERILLEPNS