Protein Info for IAI46_14610 in Serratia liquefaciens MT49

Annotation: zinc ABC transporter ATP-binding protein ZnuC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00005: ABC_tran
  • amino acids 20 to 149 (130 residues), 106.4 bits, E=2e-34

Best Hits

Swiss-Prot: 89% identical to ZNUC_YERE8: Zinc import ATP-binding protein ZnuC (znuC) from Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)

KEGG orthology group: K09817, zinc transport system ATP-binding protein [EC: 3.6.3.-] (inferred from 99% identity to spe:Spro_2774)

MetaCyc: 79% identical to Zn2+ ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-63-RXN [EC: 7.2.2.20]

Predicted SEED Role

"Zinc ABC transporter, ATP-binding protein ZnuC" in subsystem Transport of Zinc

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.-

Use Curated BLAST to search for 3.6.3.- or 7.2.2.20

Protein Sequence (252 amino acids)

>IAI46_14610 zinc ABC transporter ATP-binding protein ZnuC (Serratia liquefaciens MT49)
MSTLTTLKNISVSFGNRKVLSNISLSLQPGRILTLLGPNGAGKSTLVRVVLGLIEPTEGT
LEREPGLRIGYVPQKLHLDATLPLTVSRFMRLKPGVKKADILPALKRVHAAHLLDQPMQK
LSGGENQRVLLARALLNKPQLLVLDEPTQGVDVNGQLALYDLIDQLRKELGCAVLMVSHD
LHLVMAKTDEVLCLNQHICCSGAPEVVSMHPEFIAMFGNRGAEQLAVYRHHHNHRHDLQG
RIVLKKTGGREA