Protein Info for IAI46_14410 in Serratia liquefaciens MT49

Annotation: TonB-dependent siderophore receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 705 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details TIGR01783: TonB-dependent siderophore receptor" amino acids 65 to 705 (641 residues), 516 bits, see alignment E=8.8e-159 PF07715: Plug" amino acids 65 to 167 (103 residues), 87 bits, see alignment E=1.2e-28 PF00593: TonB_dep_Rec" amino acids 258 to 674 (417 residues), 190.9 bits, see alignment E=7.7e-60

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 93% identity to spe:Spro_2736)

Predicted SEED Role

"Ferrichrome-iron receptor" in subsystem Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (705 amino acids)

>IAI46_14410 TonB-dependent siderophore receptor (Serratia liquefaciens MT49)
MPMIFPVKRSRVLCAFAMFLPLVSFAEDTLVVTAKPADTAEAATHGYQATTSQGATKTDK
PLILTAQSVSVVTRQQMTDQNTQTVNDALKYTSGVFTNFAGGATRYDTIALRGFHGGDVN
NTFLDGLRLLSDGGTYNALQVDPWFLERIDVIKGPSSVMYGQSIPGGLVALTSKRPQFAT
EGHVNLMAGNNNTQGGAFDVTGALSEQWAYRLTGMTRSSETMYDHQREERYAISPSLLWQ
PDENTSLLLKAYLQKDPSGGYHSAVPADGSLYSSSGDKLGRGFFDGESSRNVFKRWEQIY
SYAFSHSFNDIWSFRQNASYTHSNVELQQVYQIGWNDDHSLLNRYYSGSATSLDAFAVDN
QLEADFATGLLDHKVMLGLDYQRLRNNLWDESAGASQLNPYTGVSGGDALTNLTHTDSRR
RYEQTGVYLQDEISLQNWYLNLSGRFDRIESKNTVLNTGTSDARTDDNFSGRGSLLYRFD
NGFSPYVSYSTAVTPEALPDQNGHMLKPSTSEQYEVGLKYQPPGSSSIYSVALYDLTQKD
VANRVVQQSYYLPAGKVHSQGIELEARSKITERFDLIAGYTYNKVKFKDAIDGNDGNTPY
LAPDQMASLWGKYATAYGVDLGAGARYIGKQWADNENTLRIPSVTLLDASVRMNLDRVNP
SLKGAYVQLNVNNLTDRKYVAACYGTGYCYWGAERSVVATVGYDF