Protein Info for IAI46_14015 in Serratia liquefaciens MT49

Annotation: PHP domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02811: PHP
  • amino acids 15 to 169 (155 residues), 37 bits, E=2.2e-13

Best Hits

Swiss-Prot: 73% identical to RNAAM_ECOLI: 5'-3' exoribonuclease (yciV) from Escherichia coli (strain K12)

KEGG orthology group: K07053, (no description) (inferred from 97% identity to spe:Spro_2666)

MetaCyc: 73% identical to RNase AM (Escherichia coli K-12 substr. MG1655)
RXN-16009 [EC: 3.1.3.97]; 3.1.13.- [EC: 3.1.3.97]; RXN-24047 [EC: 3.1.3.97]

Predicted SEED Role

"COG0613, Predicted metal-dependent phosphoesterases (PHP family)"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.3.97

Protein Sequence (295 amino acids)

>IAI46_14015 PHP domain-containing protein (Serratia liquefaciens MT49)
MTDSSPQPSAFTLYDLHSHTTASDGYLTPAQLVQRAVEMRVGVLAITDHDTTEGLAAAAA
TIAELSLPLQLVNGVEISTLWENHEIHIVGLGIETAHPAMVQLLAEQTERRNLRAQEIGV
RLAKARIDGAFEGAQKLADGGAVTRGHFARYLVQIGIADNMAQVFKKYLAKGKTGYVPPQ
WCTIKQAIDVIHQSGGQAVIAHPGRYDLTAKWLKRLLAHFAEQGGDAMEVAQCQQAPHER
SQLAKYAQEYQLLASQGSDFHQPCSWIELGRKLWLPGGVEPVWRDWPQPQQGKVS