Protein Info for IAI46_14000 in Serratia liquefaciens MT49

Annotation: alpha/beta hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 265 PF12697: Abhydrolase_6" amino acids 23 to 257 (235 residues), 42.2 bits, see alignment E=2.3e-14 PF00561: Abhydrolase_1" amino acids 23 to 144 (122 residues), 37.3 bits, see alignment E=3.7e-13

Best Hits

KEGG orthology group: None (inferred from 87% identity to spe:Spro_2663)

Predicted SEED Role

"1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase" in subsystem N-heterocyclic aromatic compound degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (265 amino acids)

>IAI46_14000 alpha/beta hydrolase (Serratia liquefaciens MT49)
MTAFRHGTLYLDYHDSGSGPLTLVLLPGWCEPKTVFAPFTALASQKYRVISLDWRGHALS
DRDAGLSLGAQDLLADLQQLLLELQVERFVTLSVAHASWIAVALAENMPQQMQGMVFLDW
IMTQPEPAFFDSVQQMQRPEHWLAARDDLFTFWQGGIEHPQVKQHLTVEMAQEDYRVWQA
AGVAIEQAYRQYGSPLNRLGELTSPPACRHIYSLDRGEDYLRQQQSFAANHPFFSVVRLE
NARTHLGILEQPAAVYRAVVDFLDD