Protein Info for IAI46_13730 in Serratia liquefaciens MT49

Annotation: helix-turn-helix domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 340 PF13730: HTH_36" amino acids 18 to 67 (50 residues), 44.4 bits, see alignment 1.2e-15

Best Hits

Predicted SEED Role

"Primosomal protein I" in subsystem DNA-replication

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (340 amino acids)

>IAI46_13730 helix-turn-helix domain-containing protein (Serratia liquefaciens MT49)
MSMNLMAQAMSIKVGNPLRKLVLIKIADNANDKGECWPSYQHVADHCECSKSAVRAHIEA
LIKMGLITKENRLGVNNGKGNTSNLYYLTLDTPVSSESIAPCAVKKHSPMPPKSTGLCQQ
VAPPVPSKSTPPMSPDGTRTSHSLEPVIGPKENPPIAPQSEQPATDTSGMAGEVLDFLNE
KINGKTPKRVNTLREITERLAEGNTVDELKLVAEHRVSLLLSNPAMGHMLSAKMIFDPVR
FSGYLAAANTWNVQRTRKAAMADAVEQQRQELPAGDAPEIDFDESFDRLIRDAAMPANAA
EKRAQQQVRKNGFGNVDESKARQMWRPILTRAYAMAGAQA