Protein Info for IAI46_13185 in Serratia liquefaciens MT49

Annotation: ornithine lipid synthase OlsF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 573 PF19576: Acyltransf_2" amino acids 16 to 260 (245 residues), 90.3 bits, see alignment E=1.6e-29 PF01553: Acyltransferase" amino acids 67 to 192 (126 residues), 47.9 bits, see alignment E=1.8e-16 PF13444: Acetyltransf_5" amino acids 322 to 422 (101 residues), 86.9 bits, see alignment E=2e-28

Best Hits

KEGG orthology group: None (inferred from 98% identity to srs:SerAS12_2574)

MetaCyc: 98% identical to ornithine lipid synthase (Serratia proteamaculans 568)
RXN-12431 [EC: 2.3.2.30]; RXN-12432 [EC: 2.3.2.30, 2.3.1.270]

Predicted SEED Role

"Putative hemolysin"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.3.1.270 or 2.3.2.30

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (573 amino acids)

>IAI46_13185 ornithine lipid synthase OlsF (Serratia liquefaciens MT49)
MFSLDSLLHDAFPHRNTPAWQRSLLRTLLFEKEFKQFAADYPHLKGLDLIEQVVDYFNLS
CELVDGDLENIPSQGPVVLVANHPIGSLDGLVLLRAVAAVRPDVKVVASQLLTYIEPLRS
LFVPVDNVAYKTSRKQIEGMQAQLDKQGALILFPAGEVSRMSPKGIRDGHWHTGFLRLAA
KARAPIVPIHISARNSNLFYFTSLVYRPLSTLLLVREMFQQQGGRIKIRVGGRIPFANWH
DGHTSAKDLAERFRRHVYRLGQGKEGLFASESPIALPEDRLELKKALANCERLGVTPDGK
IIFLYRRQDEARTPILRELGRLREIAFRAVGEGSGRRRDLDSYDDDYYHLVLWDADELEI
VGAYRFIPTAEQLERKGLEGIYSNSLFHYDRDMAPILAQGIELGRSFIQPAYWGKRGLDY
LWLGIGAYLAKYPQYRYLFGPVSISGGMPVTARDLLIAFYRLYFSPDSALAQSRQPYPAS
LPQVLAQFAGDNYQEDLVRLKSLLSNIGCSIPTLYKQYTELCEPGGVQFIDFGTDPAFNN
CIDGLVLVDLTRLKPARFQRYIAVHQPQEACIE