Protein Info for IAI46_13050 in Serratia liquefaciens MT49

Annotation: alpha/beta hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF20434: BD-FAE
  • amino acids 73 to 178 (106 residues), 60.6 bits, E=1.6e-20
• PF07859: Abhydrolase_3
  • amino acids 79 to 285 (207 residues), 242.2 bits, E=5.1e-76

Best Hits

KEGG orthology group: None (inferred from 85% identity to spe:Spro_2542)

Predicted SEED Role

"Esterase/lipase/thioesterase (EC 3.1.1.3)" (EC 3.1.1.3)

MetaCyc Pathways

• triacylglycerol degradation (2/3 steps found)
• retinol biosynthesis (1/7 steps found)

KEGG Metabolic Maps

• Glycerolipid metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.1.1.3

Use Curated BLAST to search for 3.1.1.3

Protein Sequence (302 amino acids)

>IAI46_13050 alpha/beta hydrolase (Serratia liquefaciens MT49)
MPLDPQIARFLAEAAQAPAPASLSEMREVAQAGLLALQGEAEASGGVRDGWVTADDGQAI
AIRAYTPGGATPGEPLPAMLYAHGGGWCLGSLALYDRPCQALANATGRVILSVDYRLAPE
YPYPRPLEDVYQALCGVVERADEWGVDVARMAVGGDSAGGNLAAAVALLARDRKGPQIEH
QLLLYPALSRAMDTASYEEYAQGYYLTREVMAFCWNTYLGEADKPQDPYAEPLHAPRLQR
LPPATILSCEYDPLRDEAELYAKRLQEAGVAVRCERLPGMVHACIHMLGLTPAARVLFDK
VG