Protein Info for IAI46_12920 in Serratia liquefaciens MT49

Annotation: diguanylate cyclase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 480 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 37 to 79 (43 residues), see Phobius details amino acids 86 to 107 (22 residues), see Phobius details amino acids 119 to 144 (26 residues), see Phobius details amino acids 161 to 181 (21 residues), see Phobius details amino acids 202 to 225 (24 residues), see Phobius details amino acids 230 to 257 (28 residues), see Phobius details amino acids 277 to 298 (22 residues), see Phobius details PF05231: MASE1" amino acids 16 to 252 (237 residues), 30.3 bits, see alignment E=2.4e-11 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 306 to 469 (164 residues), 156.6 bits, see alignment E=2.5e-50 PF00990: GGDEF" amino acids 310 to 466 (157 residues), 134.9 bits, see alignment E=2.2e-43

Best Hits

KEGG orthology group: None (inferred from 85% identity to spe:Spro_2518)

Predicted SEED Role

"GGDEF domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (480 amino acids)

>IAI46_12920 diguanylate cyclase (Serratia liquefaciens MT49)
MHTTELPGATKLQHALIVFLLVFGLCLFGIVSRPTGLLSSFWPANAVLLALLVRYPALAS
PWGWLMAILGYMAADLITGSTVVKAALLNGANITGVAVGFFLFMRLSPQVRTLERTSSSI
FLFAICLTSATATGLVGAGASVLLFDRQFLPAMALWLSSEFTHYITLMPFILTFPTDWKG
YLHSLNQAVFRRSQWYSICRKMAVLILLLVACICSVLIGGPGAVIFPMPILLWLAMTFSL
FSTMIAVLAYVLWCHFAIDMGLIATNLDMKLLQNTVSMRLGVALLALGPIAVASMNYARN
ALLRRLEHVANHDALTHVLTRSAFMQRGTKLVSQKGEHVCIMMLDIDYFKSINDRFGHAG
GDAALLSFTRAITADLRDQDLFGRMGGEEFAIVAPIAQQQDALSLAERLRRRVEIESITM
PAGTSLQITVSIGMVTCIGGSGQNLDNLLKIADLAVYKAKNSGRNRVATPELLSRAYTDL