Protein Info for IAI46_12825 in Serratia liquefaciens MT49

Annotation: substrate-binding domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 308 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF13407: Peripla_BP_4" amino acids 23 to 284 (262 residues), 175.5 bits, see alignment E=1.6e-55 PF00532: Peripla_BP_1" amino acids 63 to 237 (175 residues), 43.3 bits, see alignment E=3.3e-15

Best Hits

Swiss-Prot: 40% identical to MOCB_RHIML: Putative rhizopine-binding protein (mocB) from Rhizobium meliloti

KEGG orthology group: None (inferred from 87% identity to pao:Pat9b_4540)

Predicted SEED Role

"Inositol transport system sugar-binding protein" in subsystem Inositol catabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (308 amino acids)

>IAI46_12825 substrate-binding domain-containing protein (Serratia liquefaciens MT49)
MKKIILLCLSLLSLSPSVFAVQVGVSIAQMDDVFLSRLRGYIIERAKTHPDLKLQFEDAQ
GAVDKQLSQVQSFINGKVDVIIVNPVDTQGTKNITEAARKAKIPLIYLNRMPSDSTMGNG
ISYIGSDEIEAGRLQMQYLAEMVKDRKSVNVAIMKGLLSNDATRFRTQGAKEIIAKNPNM
HVILEDTAKWMREDGMNLMNNWILSGDKIDILSSNADEMAIGAAMAIKSNGKSVGKDILI
GGTDGGPNGLQAIKKGMLTVTVFQDAKSQAYGAVDMAEQAAKGEAIKDMNFIPFQLVTPQ
NYEKFMTP