Protein Info for IAI46_12760 in Serratia liquefaciens MT49

Annotation: DMT family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 303 transmembrane" amino acids 7 to 29 (23 residues), see Phobius details amino acids 36 to 57 (22 residues), see Phobius details amino acids 68 to 87 (20 residues), see Phobius details amino acids 94 to 115 (22 residues), see Phobius details amino acids 123 to 139 (17 residues), see Phobius details amino acids 151 to 172 (22 residues), see Phobius details amino acids 182 to 204 (23 residues), see Phobius details amino acids 210 to 231 (22 residues), see Phobius details amino acids 239 to 260 (22 residues), see Phobius details amino acids 266 to 286 (21 residues), see Phobius details PF00892: EamA" amino acids 7 to 138 (132 residues), 47 bits, see alignment E=1.5e-16 amino acids 153 to 283 (131 residues), 66.6 bits, see alignment E=1.3e-22

Best Hits

KEGG orthology group: None (inferred from 83% identity to spe:Spro_2488)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (303 amino acids)

>IAI46_12760 DMT family transporter (Serratia liquefaciens MT49)
MKIRTGGVLQMTLAMVISGTVGWPVMLLGQPPATVVFWRCAFGALAMLIACALLGLLKKD
MLTRRQAAIAVLGGVALVLNWVMLFGAYSHASIAVATVTYHVQPFMLVGLGVLFFGEKMT
ATKFGWLVLAFVGMLLIISGKQDGGDSSADYFTGVLLALGAAFMYAVAAAIVKRLKGVPP
HLIVLIQLTLGVVLLAPFAGWAQLPSTANGWLLLATLGLVHTGLMSSLLYSAIQKIPTAL
VGALSFIYPLVAIIVDWAVFGHRLSLMQLSGAAAILLAAAGMNFGWRLVRARKPVRVVGD
QQP