Protein Info for IAI46_12650 in Serratia liquefaciens MT49

Annotation: TonB-dependent copper receptor

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 686 signal peptide" amino acids 1 to 35 (35 residues), see Phobius details PF07715: Plug" amino acids 61 to 163 (103 residues), 49.5 bits, see alignment E=5.7e-17 TIGR01778: TonB-dependent copper receptor" amino acids 64 to 686 (623 residues), 838 bits, see alignment E=3.2e-256 PF00593: TonB_dep_Rec" amino acids 217 to 646 (430 residues), 150.9 bits, see alignment E=1.1e-47

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 92% identity to spe:Spro_2454)

Predicted SEED Role

"Putative membrane receptor protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (686 amino acids)

>IAI46_12650 TonB-dependent copper receptor (Serratia liquefaciens MT49)
MMFGKTNNYKKRPLSLHITAAMPLFVLAGFNAHAAQQHQHEVAVKANDGDVITVTAPLYS
PMTIVTSPKTPRQPVPASDGSDYLKTIPGFSQIRNGGTNGDPVFRGMFGSRLKILTDGGE
MLGACPSRMDAPTSYISPESYDLLTITKGPQTVLWGAGSSAGTVRFERERPQFDKPGVKG
NASMLAGSNGRWDENIDASLGGEQGYLRLMGNKSRSHDYQDGNGDRVPSRWDKWNGDLAL
GWTPDTDTLLEVTMGRGNGEARYAGRSMDGSQFKRESLGMRVEKSNIGEVFDKLEAQVYY
NYANHIMDNTTLRSPGQGGMAMGHMGMGMPMHAGMTMQLDRRTVGGRVMGTWLWQDFKLE
SGMDTQTNTHRNKRGNAWQEDAQFHNYGAFGELTWSATEQSKIISGARLDRTLVDNYKTG
NDTERSDTLPSGFSRIEHTLAGMPLMLYAGIGYTERFPDYWELFSPTFGPGGNKSAFDSV
KSEKTTQIDIGAQYTDKRFNSWVSAYVGHVNDFILFKYDPHHARISQADNVNATIMGGEM
GMGYQLTEHWKTDASLAYAWGKNTSDNQPLPQIPPLEARFGLTYERGDWSSTGLWRVVSS
QHRVAINQGNVVGKDFADSPGFGVLSANVAYKVNSHVKLSTGLDNILNKTYSEHLNLAGN
STFGYSSNTSVNEPGRTLWAKVNVTF