Protein Info for IAI46_12625 in Serratia liquefaciens MT49

Annotation: NADH:flavin oxidoreductase/NADH oxidase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 407 PF00724: Oxidored_FMN" amino acids 1 to 333 (333 residues), 166.4 bits, see alignment E=5.4e-53

Best Hits

KEGG orthology group: None (inferred from 64% identity to rsl:RPSI07_mp1479)

Predicted SEED Role

"2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34)" (EC 1.3.1.34)

Isozymes

Compare fitness of predicted isozymes for: 1.3.1.34

Use Curated BLAST to search for 1.3.1.34

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (407 amino acids)

>IAI46_12625 NADH:flavin oxidoreductase/NADH oxidase family protein (Serratia liquefaciens MT49)
MFTPLTLPNGSVLPNRLAKAAMEENMADVGQVPGPALYRLYQSWAQGGVGLIITGNVMID
SRAMTGPGGVALEANTPLAPFTAWAKSARQNGAQVWMQINHPGRQVMASMGGEAWAPSAV
PVEMGKHSKLFAQPTAMSQAQIDEVIERFATTAYAAEQAGFTGVQIHAAHGYLLSQFLSP
LTNRRNDQWGGSLANRARLLLEVVRAVRERVSPSFCVSIKLNSADFQRGGFSEEDAQQVI
LLLNELPVDLIELSGGSYESPAMQGNAADGRTLAREAYFLEFARDLAAVAHMPVMTTGGI
ARKSVAQQVLDSGVAVAGIATAMAQVPDLPLQWKAGNEPYALPKPVTWKNKTMAGLARMA
LVTRRLRALGEGRTRASRYSPLFTLIINQLRTKRITRRYRQWRQQRA