Protein Info for IAI46_12110 in Serratia liquefaciens MT49

Annotation: beta-lactamase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 390 transmembrane" amino acids 59 to 78 (20 residues), see Phobius details PF00144: Beta-lactamase" amino acids 12 to 363 (352 residues), 222 bits, see alignment E=6.1e-70

Best Hits

KEGG orthology group: None (inferred from 87% identity to srs:SerAS12_2327)

Predicted SEED Role

"Beta-lactamase class C and other penicillin binding proteins" in subsystem Beta-lactamase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (390 amino acids)

>IAI46_12110 beta-lactamase family protein (Serratia liquefaciens MT49)
MNKYKLDAKAIDKAIDLALEQKRLVGAVVLVALGGEQVYRRAAGMADREAGKPMRIDALF
RLASVSKPILSTAALVLMAQGRLRLEDPVARWLPSFRPRTPDGQQPIVTVRHLMTHTAGL
SYRFFQPEHGSYAQAGVSDGMDDDPLSLAENVRRIASAPLQAAPGTEWRYSIATDVLGAV
IEQASGLPLAQAVAHLVTGPIAMRDTGFSTHDAQRLTVAYANHYPEPRPLQQPDRIEFID
GTDGFKLSPARALDASAYASGGAGMVGSAEDFLRLLETLRRGGSPLLPEEWVTAMTSNQI
GDLPMPFWPGRGFGLGITVLKDPRAAQTPESVGTWRMGGTYGHSWFVDPARQLSVVAFTN
TALEGMAGAFVGELCQAVYDGLPLLAGDQC