Protein Info for IAI46_12080 in Serratia liquefaciens MT49
Annotation: amino acid ABC transporter ATP-binding protein
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 54% identical to TCYC_BACSU: L-cystine import ATP-binding protein TcyC (tcyC) from Bacillus subtilis (strain 168)
KEGG orthology group: K02028, polar amino acid transport system ATP-binding protein [EC: 3.6.3.21] (inferred from 96% identity to spe:Spro_2361)Predicted SEED Role
"Amino acid ABC transporter, ATP-binding protein"
Isozymes
Compare fitness of predicted isozymes for: 3.6.3.21
Use Curated BLAST to search for 3.6.3.21
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (253 amino acids)
>IAI46_12080 amino acid ABC transporter ATP-binding protein (Serratia liquefaciens MT49) MSAAIQINQVRKSFSGTEVLKNISLQIPAGSVTVILGPSGSGKSTLLRCINHLEKLDGGT IRVGEQLIGYRQKGNQLYELKEREVAEQRKSIGMVFQQFNLFPHRTVLENVTEAPLLVKK EKKSLVVERAKALLARVGLEHRIHAWPRELSGGQQQRVAIARALAMTPEVLLFDEPTSAL DPELVGEVLQVMKGLAHSGMTMVVVTHEIGFAREVADQIIFMDQGKVVETGTAKQVLDEP VHQRTRDFLATVL