Protein Info for IAI46_11775 in Serratia liquefaciens MT49

Annotation: ROK family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 391 PF13412: HTH_24" amino acids 15 to 58 (44 residues), 22.4 bits, see alignment 1.1e-08 PF00480: ROK" amino acids 87 to 375 (289 residues), 141 bits, see alignment E=8.7e-45

Best Hits

KEGG orthology group: None (inferred from 97% identity to spe:Spro_2298)

Predicted SEED Role

"Mlc, transcriptional repressor of MalT (the transcriptional activator of maltose regulon) and manXYZ operon" in subsystem Maltose and Maltodextrin Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (391 amino acids)

>IAI46_11775 ROK family transcriptional regulator (Serratia liquefaciens MT49)
MTTSGTNLEHARAHNRRVVIEAIRLHGELTRAEIARLTSLTPQTVSNIATELEQAGILSS
HLPRRAGGRGQPATPLTLNPDSAYSIGIHLDHQSLLMIVVDLSGSVRFHRLIMVQKPQPA
ATLKLICDVLQEMRQQPDLAWGKMLGIGVVMPGPFGVEGISSVGPTTLNGWENIDVVAEL
NAQSGLPVTLENDATVAAIGERLHGVARQLNSFIYLYLGTGLGAGIFTDGRIYTGHAHNA
GEVGHMIVQPGGRACYCGNQGCLERYVSLQAAYESCGLDPMSARPQDLLALPQSQIDAWL
DSAVPALRQAINIVECMFDAEAVIIGGLMPESLVAQLIKRLAPLHRSVRSKYLDGLRVRL
GTTGADTAALGAAALPLFDEFNPRYEVLLKS