Protein Info for IAI46_11770 in Serratia liquefaciens MT49

Annotation: extracellular solute-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 416 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF01547: SBP_bac_1" amino acids 46 to 333 (288 residues), 154.5 bits, see alignment E=6.7e-49 PF13416: SBP_bac_8" amino acids 48 to 355 (308 residues), 114.7 bits, see alignment E=6.9e-37

Best Hits

KEGG orthology group: K02027, multiple sugar transport system substrate-binding protein (inferred from 98% identity to spe:Spro_2297)

Predicted SEED Role

"Glucosamine ABC transport system, periplasmic sugar-binding protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (416 amino acids)

>IAI46_11770 extracellular solute-binding protein (Serratia liquefaciens MT49)
MKSHTLAATAVCTLSALALSLSSAYAAPTQISALFMTQAAYSENDIRAMTADFSKQHPDI
TVNLEFVPYEALHDKIVAARGAGSNGYDVVLFDAIWPAEFTKFGLLQDVTARISADDSAK
IFAGAMTTVTYKDKRWGMPWILDTKYLYYNKAMLAKAGIAAPPKTWQELEQQAEILKQKN
VVKYPLVWSWSQAEALVCDYTTLVSAFKGQFIQQGKITFSSPGSLQAASYMKASLDKGLT
NPNSREYLEEDVRKAFSNGDAAFALNWTYMYNMANDPKQSKVAGDVGIVPAPGSEAGQVS
AVNGSMGLGIAKASAHPDQAWQYISYMTSQPVQDKYAKLSLPIWKSSYEDPAVQKGQEPL
IAAAKQSLNVMLSRPETADYSRLSNGLQQDLQQILQGKVTPQAGLDAATQSAARLR