Protein Info for IAI46_11605 in Serratia liquefaciens MT49

Annotation: Mal regulon transcriptional regulator MalI

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 343 PF00356: LacI" amino acids 7 to 52 (46 residues), 61.3 bits, see alignment 1.2e-20 PF00532: Peripla_BP_1" amino acids 64 to 338 (275 residues), 204.2 bits, see alignment E=6.2e-64 PF13407: Peripla_BP_4" amino acids 66 to 258 (193 residues), 50.7 bits, see alignment E=3.7e-17 PF13377: Peripla_BP_3" amino acids 174 to 342 (169 residues), 79.4 bits, see alignment E=6.9e-26

Best Hits

Swiss-Prot: 56% identical to MALI_ECOLI: Maltose regulon regulatory protein MalI (malI) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 96% identity to spe:Spro_2271)

Predicted SEED Role

"Maltose regulon regulatory protein MalI (repressor for malXY)" in subsystem Maltose and Maltodextrin Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (343 amino acids)

>IAI46_11605 Mal regulon transcriptional regulator MalI (Serratia liquefaciens MT49)
MTIKKITITDVAQQAGVSVTTVSLVLSGKGRISSTTVTRVNQAIESLGYVRNRQAATLRG
GESGVIGLILRDICEPFYAEMTAGLSEVLEEHGKVLFLTQSGRDGKGLMRCFDTLLEHGV
DGMVLAGGVRMAEGLKEKAAEQGVPLVCAARSNGLDGVDVVRPDNMQAAKLATEFLIKRG
HSQIAYLGGQSSSLTRAERLGGFCATLVQYGLPFRTEWIVECDCQQRAAAEAAENLLRQY
PNISALVCHKASVALGAYFGIVRSGRSIGSEGVDTYYGQQVALIGFGDVPEAELTEPPLT
LVSSSAREVGRSAASRLLQRIADTGLPPQNVILPPMLIKRGSA