Protein Info for IAI46_11515 in Serratia liquefaciens MT49

Annotation: L-arabinose ABC transporter ATP-binding protein AraG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 511 PF00005: ABC_tran" amino acids 23 to 172 (150 residues), 126.5 bits, see alignment E=1.2e-40 amino acids 274 to 427 (154 residues), 69.6 bits, see alignment E=4.4e-23

Best Hits

Swiss-Prot: 84% identical to ARAG_YERPN: Arabinose import ATP-binding protein AraG (araG) from Yersinia pestis bv. Antiqua (strain Nepal516)

KEGG orthology group: K10539, L-arabinose transport system ATP-binding protein [EC: 3.6.3.17] (inferred from 95% identity to spe:Spro_2246)

MetaCyc: 79% identical to arabinose ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-2-RXN [EC: 7.5.2.12, 7.5.2.13]

Predicted SEED Role

"L-arabinose transport ATP-binding protein AraG (TC 3.A.1.2.2)" in subsystem L-Arabinose utilization (TC 3.A.1.2.2)

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.17

Use Curated BLAST to search for 3.6.3.17 or 7.5.2.12 or 7.5.2.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (511 amino acids)

>IAI46_11515 L-arabinose ABC transporter ATP-binding protein AraG (Serratia liquefaciens MT49)
MTTALPYLAFKGIGKTFPGVKALDDISFSCQAGQIHALMGENGAGKSTLLKILSGNYSPT
QGEIQLQGRSVTFANTTDALDAGVAIIYQELHLVPEMTVAENIYLGQLPTRRGLVDRKLL
RYESRLQLEHLGLDIDPDTPLKYLSIGQWQMVEIAKALARNAKVIAFDEPTSSLSAREIE
QLFRVIRELRAEGRVILYVSHRMEEIFALSDAITVFKDGRYVRTFDDMRQVDNAQLVQAM
VGRDLGDVYGYQPRELGPVRLALRGLQAPGVKTPIDLSVRAGEIVGLFGLVGAGRSELMK
GIFGATRVSAGQLMLDGQVLAIRSPIDAIRAGIMLCPEDRKADGIIPVHSVRDNINISAR
RNSVRAGCLIDNGWEASNAEHHIRALNIKTPSAEQLIMNLSGGNQQKAILGRWLSEDMKV
ILLDEPTRGIDVGAKHEIYNVIYQLAQRGIAVLFASSDLPEVLGLADRILVMREGALSGE
LLHDDASEEKALSLAMLRTPEIAPDTAAAVA