Protein Info for IAI46_11500 in Serratia liquefaciens MT49

Annotation: L-arabinose isomerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 501 PF02610: Arabinose_Isome" amino acids 5 to 359 (355 residues), 596 bits, see alignment E=2.8e-183 PF11762: Arabinose_Iso_C" amino acids 363 to 476 (114 residues), 158.6 bits, see alignment E=5e-51

Best Hits

Swiss-Prot: 94% identical to ARAA_SERP5: L-arabinose isomerase (araA) from Serratia proteamaculans (strain 568)

KEGG orthology group: K01804, L-arabinose isomerase [EC: 5.3.1.4] (inferred from 94% identity to spe:Spro_2243)

MetaCyc: 74% identical to L-arabinose isomerase (Escherichia coli K-12 substr. MG1655)
L-arabinose isomerase. [EC: 5.3.1.4]

Predicted SEED Role

"L-arabinose isomerase (EC 5.3.1.4)" in subsystem L-Arabinose utilization (EC 5.3.1.4)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.3.1.4

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (501 amino acids)

>IAI46_11500 L-arabinose isomerase (Serratia liquefaciens MT49)
MDAFKQREVWFAIGSQHLYGPHTLQQVKAHAEQVVENLNREAGLPVKLVLKPLVTTPDEI
TALCRDANYQPQCIGIMAWLHTFSPAKMWIAGLSILHKPLLQFHTQFNAQIPWDSMDMDF
MNLNQTAHGGREFGFIGARMRQQHSVIAGHWQDPEAHRRIAQWMRAANAKQASQQLKVAR
FGDNMREVAVTEGDKVGAQIQFGYSVNAYGIGDLVSVINEVSRGDVDTLIEEYETRYVLS
DAAQINGEKRENLLDAARIELGMKRFLEQGNFQAFTTNFEDLHGMKQLPGLAVQRLMQQG
YGFGGEGDWKTAALLRILKVMAQGLEGGTSFMEDYTYHFQSGNDLVVGSHMLEVCPSIAK
EQKPLLDIQPLGIGGKADPARLIFSTPAGPAINASLIDLGDRFRLLVNQVDTVEQPHPLP
KLPVARAIWRAQPTLATAAEAWILAGGAHHTVFSQALNADLLRLYAEMHNIEFVTIDHST
SLPAFKNELRWNEAYYQLNRR