Protein Info for IAI46_11310 in Serratia liquefaciens MT49

Annotation: aldo/keto reductase family oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 298 PF00248: Aldo_ket_red" amino acids 17 to 291 (275 residues), 154.4 bits, see alignment E=1.9e-49

Best Hits

Swiss-Prot: 76% identical to YDHF_ECOLI: Oxidoreductase YdhF (ydhF) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 94% identity to srs:SerAS12_2149)

Predicted SEED Role

"Putative aldo/keto reductase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (298 amino acids)

>IAI46_11310 aldo/keto reductase family oxidoreductase (Serratia liquefaciens MT49)
MENRIQLAPQGPEFSRMICGYWRLMEWGMSPQQLLAFIEQHIELGVTTADHADIYGGYAC
EQAFGEAMRLKPSLRQSMELVSKCGIATTAKPGNAIGHYITDREHIVYSAERSLAHLHTD
YLDLLLIHRPDPLMDADEVAEAFVSLHQSGKVRHFGVSNFTPAQFTLLQSRLPFSLVTNQ
LEISPIHQPSILDGSLDQCQQLRIKPMAWSCLGGGRLFSDAEFQPLRDELQAVAQEIGAE
TIEQVVYAWVMRLPSAPLPIIGSGKIERVRSALKAQQLTLDRQQWFRIRKAALGYDVP