Protein Info for IAI46_11250 in Serratia liquefaciens MT49

Annotation: superoxide dismutase [Fe]

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 192 PF00081: Sod_Fe_N" amino acids 2 to 82 (81 residues), 111.2 bits, see alignment E=2.7e-36 PF02777: Sod_Fe_C" amino acids 89 to 190 (102 residues), 141.3 bits, see alignment E=9.5e-46

Best Hits

Swiss-Prot: 77% identical to SODF_SALTY: Superoxide dismutase [Fe] (sodB) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: K04564, superoxide dismutase, Fe-Mn family [EC: 1.15.1.1] (inferred from 93% identity to spe:Spro_2196)

MetaCyc: 76% identical to superoxide dismutase (Fe) (Escherichia coli K-12 substr. MG1655)
Superoxide dismutase. [EC: 1.15.1.1]

Predicted SEED Role

"Superoxide dismutase [Fe] (EC 1.15.1.1)" in subsystem Oxidative stress (EC 1.15.1.1)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 1.15.1.1

Use Curated BLAST to search for 1.15.1.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (192 amino acids)

>IAI46_11250 superoxide dismutase [Fe] (Serratia liquefaciens MT49)
MSFELPALPYEKNALEPHISAETLEYHYGKHHNAYVVNLNNLLKGSEFEGLSLEAIIKAS
SGGIFNNAAQVWNHTFYWHCLSPQGGGEPQGKLAAAINQAFGSFTAFREQFSDAAVKNFG
AGWTWLVKKPDGSLAIVNTSNAATPLTGEDKPLLTVDVWEHAYYIDYRNARPAYLENFWA
LVNWAFVEENLA