Protein Info for IAI46_10885 in Serratia liquefaciens MT49

Annotation: manganese/iron ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 296 PF00005: ABC_tran" amino acids 28 to 174 (147 residues), 111.3 bits, see alignment E=5.9e-36 PF13304: AAA_21" amino acids 138 to 206 (69 residues), 30.7 bits, see alignment E=3.3e-11

Best Hits

Swiss-Prot: 83% identical to YFEB_YERPE: Chelated iron transport system membrane protein YfeB (yfeB) from Yersinia pestis

KEGG orthology group: K11607, manganese/iron transport system ATP-binding protein (inferred from 98% identity to spe:Spro_2132)

Predicted SEED Role

"Manganese ABC transporter, ATP-binding protein SitB" in subsystem Transport of Manganese

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (296 amino acids)

>IAI46_10885 manganese/iron ABC transporter ATP-binding protein (Serratia liquefaciens MT49)
MTSEVFVRPELSVDDVTVTYNNGHTAIHNASFTLSGGAICALVGVNGSGKSTLFKSIMGL
VRPTTGRVQLNEQPVAQALKKNVIAYVPQTEDVDWNFPVLVEDVVMMGRYGKMNFLRIPS
KEDRLRVDKALERVGLSELRTRQIGELSGGQKKRVFLARALAQQGSVLLLDEPFTGVDVK
TENAIIDLLRALRDEGHLILVSTHNLGSVPEFCDRVILINRTVLAAGPTETTFTQSNLEQ
AFGGVLRHINLSGPDLHDDNDPRTVTVLTDDERPAVFYGHTKSDPPAQSQPKEKQP