Protein Info for IAI46_10845 in Serratia liquefaciens MT49

Annotation: metal-dependent hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 182 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 30 to 47 (18 residues), see Phobius details amino acids 69 to 90 (22 residues), see Phobius details amino acids 104 to 129 (26 residues), see Phobius details amino acids 150 to 171 (22 residues), see Phobius details PF04307: YdjM" amino acids 1 to 162 (162 residues), 128.9 bits, see alignment E=7.2e-42

Best Hits

Swiss-Prot: 71% identical to YDJM_ECOLI: Inner membrane protein YdjM (ydjM) from Escherichia coli (strain K12)

KEGG orthology group: K07038, inner membrane protein (inferred from 99% identity to spe:Spro_2124)

Predicted SEED Role

"Membrane-bound metal-dependent hydrolase YdjM, induced during SOS response"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (182 amino acids)

>IAI46_10845 metal-dependent hydrolase (Serratia liquefaciens MT49)
MTAEGHLIFSVACAIFAKKAEVTPELATGDWWHIIPAALLTSLLPDIDHPKSVLGQRLRW
IAIPISRAFGHRGFTHSLLAIAGGMALFQLDVPRSWPIPADVLHAMIIGYFSHLLADMLT
PAGVPLLWPCRWRFRLPLLNSQKGNQLERALCLCLVAFAIYWQGGCTIPVQSYFEQIKNI
RL