Protein Info for IAI46_10470 in Serratia liquefaciens MT49

Annotation: AI-2E family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 373 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details transmembrane" amino acids 30 to 47 (18 residues), see Phobius details amino acids 59 to 85 (27 residues), see Phobius details amino acids 152 to 176 (25 residues), see Phobius details amino acids 212 to 233 (22 residues), see Phobius details amino acids 239 to 268 (30 residues), see Phobius details amino acids 276 to 297 (22 residues), see Phobius details amino acids 320 to 342 (23 residues), see Phobius details PF01594: AI-2E_transport" amino acids 11 to 339 (329 residues), 166.4 bits, see alignment E=5e-53

Best Hits

KEGG orthology group: None (inferred from 94% identity to spe:Spro_2050)

Predicted SEED Role

"membrane protein, putative"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (373 amino acids)

>IAI46_10470 AI-2E family transporter (Serratia liquefaciens MT49)
MMSKGISKGFFLLILFIVTAAFMDVLGPYYSSVLWAIILAVIFHPVKQKLKQYLGDRNGL
VSLITLAVICLIVFTPLAIIASSLAIELNVVYTKLQTNNTQFPVIVADTLKLLPGWARHF
LAEHNLDSAAEIQKQLSEVALKGGQYLAGSVFLIGKGTFNFAVGFGVMLYLLFFLLKDGP
YLVNLTLEALPLSQHVKHHLFVKFAAVSRATVKGTVVVAVVQGALGGLAFYFTGIDGSLL
WGALMAFLSIIPAVGSAIIWVPAAIYFFATGMLWKGLFLVGFFVVIIGLVDNILRPLLVG
KDTKMPDYLILISTLGGMEIYGINGFVIGPLIAALFIACWNILSGRDSAETTDEIDEDFI
EEGKNHPDATKAE