Protein Info for IAI46_10435 in Serratia liquefaciens MT49

Annotation: high frequency lysogenization protein HflD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 208 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF04356: DUF489" amino acids 7 to 198 (192 residues), 256 bits, see alignment E=1.4e-80

Best Hits

Swiss-Prot: 95% identical to HFLD_SERP5: High frequency lysogenization protein HflD homolog (hflD) from Serratia proteamaculans (strain 568)

KEGG orthology group: K07153, high frequency lysogenization protein (inferred from 95% identity to spe:Spro_2021)

Predicted SEED Role

"FIG002903: a protein of unknown function perhaps involved in purine metabolism"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (208 amino acids)

>IAI46_10435 high frequency lysogenization protein HflD (Serratia liquefaciens MT49)
MAKNYYDITLAMAGISQAALMVQQLAHEGQCDREAFHTSLNSLLQMDPSSTLAVFGGEER
NLKVGLETLMSVLNANNKGLGAELTRYTISLMVLERKLNANNQAMNQLGERLGQLERQLA
HFDLESDTIISALAGIYVDVVSPLGPRIQVTGSPAILQNPQVQAKVRATLLAGIRAAVLW
QQVGGSRLQLMFSRNRLFKQAQNIVAHC