Protein Info for IAI46_10345 in Serratia liquefaciens MT49

Annotation: lipoprotein-releasing ABC transporter permease subunit LolE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 415 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details transmembrane" amino acids 27 to 49 (23 residues), see Phobius details amino acids 271 to 295 (25 residues), see Phobius details amino acids 316 to 344 (29 residues), see Phobius details amino acids 356 to 372 (17 residues), see Phobius details amino acids 378 to 399 (22 residues), see Phobius details TIGR02213: lipoprotein releasing system, transmembrane protein LolE" amino acids 5 to 415 (411 residues), 724.4 bits, see alignment E=3.6e-222 TIGR02212: lipoprotein releasing system, transmembrane protein, LolC/E family" amino acids 6 to 414 (409 residues), 528.2 bits, see alignment E=1.5e-162 PF12704: MacB_PCD" amino acids 28 to 239 (212 residues), 67.6 bits, see alignment E=1.9e-22 PF02687: FtsX" amino acids 275 to 408 (134 residues), 71 bits, see alignment E=8.7e-24

Best Hits

Swiss-Prot: 83% identical to LOLE_ECOLI: Lipoprotein-releasing system transmembrane protein LolE (lolE) from Escherichia coli (strain K12)

KEGG orthology group: K09808, lipoprotein-releasing system permease protein (inferred from 100% identity to spe:Spro_2003)

MetaCyc: 83% identical to lipoprotein release complex - inner membrane subunit (Escherichia coli K-12 substr. MG1655)
RXN-22427

Predicted SEED Role

"Lipoprotein releasing system transmembrane protein LolE"

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (415 amino acids)

>IAI46_10345 lipoprotein-releasing ABC transporter permease subunit LolE (Serratia liquefaciens MT49)
MAGASLSFLTALRFSRGRKRGGMVSLISVISTIGIALGVAVLIVGLSAMNGFERELKNRI
LAVVPHGEIEPVKQPFKDWSSILQRVEKVPGILAAAPYINFTGLMENGAQLRAVGVKGVD
PQQENQLSALPKYVQGDAWANFKSGEQQVILGKGVADALGVKQGSYVTVMIPNSDPQMKL
LQPKRIRLHVTGILQLSGQLDHSLAMVPLADAQQYLDMGDSVTGIAIKVNDVFAANKLVR
DAGEVTNSYVYIKSWIGTYGYMYRDIQMIRAIMYLAMVLVIGVACFNIVSTLVMAVKDKS
GDIAVLRTLGAKDGFIRAIFIWYGLLAGLVGSLSGVVVGVIASLQLTNIIKGLEKLMGHS
FLSGDIYFIDFLPSELHWLDVVIVLVTALVLSLLASWYPARRASRIDPARVLSGQ