Protein Info for IAI46_10335 in Serratia liquefaciens MT49

Annotation: lipoprotein-releasing ABC transporter permease subunit LolC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 transmembrane" amino acids 23 to 48 (26 residues), see Phobius details amino acids 268 to 291 (24 residues), see Phobius details amino acids 312 to 338 (27 residues), see Phobius details amino acids 357 to 382 (26 residues), see Phobius details TIGR02212: lipoprotein releasing system, transmembrane protein, LolC/E family" amino acids 4 to 400 (397 residues), 470 bits, see alignment E=3.3e-145 PF12704: MacB_PCD" amino acids 27 to 212 (186 residues), 54.4 bits, see alignment E=2e-18 PF02687: FtsX" amino acids 270 to 392 (123 residues), 65.9 bits, see alignment E=3.3e-22

Best Hits

Swiss-Prot: 81% identical to LOLC_ECO57: Lipoprotein-releasing system transmembrane protein LolC (lolC) from Escherichia coli O157:H7

KEGG orthology group: K09808, lipoprotein-releasing system permease protein (inferred from 99% identity to spe:Spro_2001)

MetaCyc: 81% identical to lipoprotein release complex - inner membrane subunit (Escherichia coli K-12 substr. MG1655)
RXN-22427

Predicted SEED Role

"Lipoprotein releasing system transmembrane protein LolC"

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (400 amino acids)

>IAI46_10335 lipoprotein-releasing ABC transporter permease subunit LolC (Serratia liquefaciens MT49)
MYQPVALFIGLRYMRGRASDRFGRFVSWLSTIGITLGVMALVTVLSVMNGFEKDLENNIL
GLMPQALITSPQGSINPQQIPASAVQSLQGVSRVAPLTTGDVVLQSARSVAVGVMLGVNP
DEADPLTPFLVNVKQQLLQPGQYNIIIGEQLAGQLGVKRGDPLRVMVPSASQFTPMGRIP
IQRLFTVVGTFHANSEVDGTQMLVNQQDASRLLRYPAGNITGWRLFLQQPLTVDTLSQQK
LPQGTEWKDWRERKGELFQAVRMEKNMMGLLLSLIVAVAAFNIITSLGLLVMEKQGEVAI
LQTQGLTRRQIMSVFMVQGASAGIIGSLLGTLLGVLLASNLNNLMPILGALIDGASLPVA
VAPLQVTIIAVAAMAVSLLSTLYPSWRAAAVQPAEALRYE