Protein Info for IAI46_10305 in Serratia liquefaciens MT49

Annotation: C4-dicarboxylic acid transporter DauA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 562 transmembrane" amino acids 33 to 53 (21 residues), see Phobius details amino acids 60 to 80 (21 residues), see Phobius details amino acids 100 to 121 (22 residues), see Phobius details amino acids 130 to 151 (22 residues), see Phobius details amino acids 173 to 199 (27 residues), see Phobius details amino acids 210 to 230 (21 residues), see Phobius details amino acids 280 to 303 (24 residues), see Phobius details amino acids 324 to 344 (21 residues), see Phobius details amino acids 350 to 369 (20 residues), see Phobius details amino acids 374 to 392 (19 residues), see Phobius details amino acids 412 to 441 (30 residues), see Phobius details TIGR00815: sulfate permease" amino acids 18 to 556 (539 residues), 445.1 bits, see alignment E=1.8e-137 PF00916: Sulfate_transp" amino acids 29 to 415 (387 residues), 268.4 bits, see alignment E=8.8e-84 PF01740: STAS" amino acids 457 to 556 (100 residues), 45.3 bits, see alignment E=6.4e-16

Best Hits

Swiss-Prot: 74% identical to DAUA_ECO57: C4-dicarboxylic acid transporter DauA (dauA) from Escherichia coli O157:H7

KEGG orthology group: K03321, sulfate permease, SulP family (inferred from 98% identity to spe:Spro_1995)

MetaCyc: 74% identical to aerobic C4-dicarboxylate transporter DauA (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-121; TRANS-RXN-122A; TRANS-RXN0-553

Predicted SEED Role

"Putative sulfate permease"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (562 amino acids)

>IAI46_10305 C4-dicarboxylic acid transporter DauA (Serratia liquefaciens MT49)
MKTHEINGIRPFSALIDACWRDPYSLQRLLKDAIAGVTVGIIAIPLAMALAIASGVPPQY
GLYTSAVAGIVIAISGGSRYSVSGPTAAFVVILYPVSQQFGLSGLLIATLLSGLFLVIMG
LARFGRLIEYIPLSVTLGFTSGIAITIATMQVKDFFGLQMAVVPEHYVGKVYALLQALPT
LDFGDTLIGAVTLLILIFWPKLGLRVPGHLPALLAGTAVMGILALFDHPVATIGSRFSYL
LADGTHGQGIPPILPQLMLPWDLPAGDGKPMALSWQTLSALLPAAFSMAMLGAIESLLCA
VVLDGMTGKKHNSNTELIGQGAGNIIAPFFGGITATAAIARSAANVRAGATSPVSAIIHA
LLVLLALLVLAPWLSWLPLAAMASLLLMVAWNMSEAHKVVYLLRRAPKDDILVMLLCMSL
TVLFDMVIAITVGIVLASLLFMRRIARMTRLSELNADNGRLVLRVNGPLFFAAAERIFNE
LLVRSESYDVIVLQWDAVPVLDAGGLDALQRFIEALPAGKQLAITDMPFQPLKTLARARI
QPIEGKLHFYATLPEALAALDA