Protein Info for IAI46_10105 in Serratia liquefaciens MT49

Annotation: sugar ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 305 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details PF00532: Peripla_BP_1" amino acids 23 to 250 (228 residues), 54 bits, see alignment E=2.8e-18 PF13407: Peripla_BP_4" amino acids 24 to 282 (259 residues), 193.7 bits, see alignment E=6.6e-61 PF13458: Peripla_BP_6" amino acids 50 to 260 (211 residues), 35.5 bits, see alignment E=1.4e-12

Best Hits

Swiss-Prot: 50% identical to MOCB_RHIML: Putative rhizopine-binding protein (mocB) from Rhizobium meliloti

KEGG orthology group: None (inferred from 95% identity to srs:SerAS12_1920)

Predicted SEED Role

"Ribose/xylose/arabinose/galactoside ABC-type transport systems, substrate-binding component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (305 amino acids)

>IAI46_10105 sugar ABC transporter substrate-binding protein (Serratia liquefaciens MT49)
MKYLKRIVLVAALSCSTSVLAETIGVSMAYFDQNFLTIIRHSIDKEAKARGITVQFEDAR
GDVGRQTDQVQSFISAGVDAIIVDPVNSAGTPAITKLVTRAGIPLVYVNRTPGDSTLPSG
VVFVGSDEKQSGTLQMEELARLANYQGNVAIMIGNLTDAGALQRTKDVEQVVAKYPKMKV
VQKQSANYSRSEGMDLMLNWVTNGESIDIVAANNDEMAIGAIMALQQAGKKDNKVLIGGI
DATPDGLKALSSGKMQVTVFQDAVGQGKASVDVAQRMIKGEKLEPYYWIPFELVTPANMQ
KYAAK