Protein Info for IAI46_10095 in Serratia liquefaciens MT49

Annotation: sugar ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 494 PF00005: ABC_tran" amino acids 21 to 170 (150 residues), 120.3 bits, see alignment E=1.4e-38 amino acids 270 to 424 (155 residues), 85.8 bits, see alignment E=6.5e-28

Best Hits

Swiss-Prot: 60% identical to RGMG_HAHCH: Putative ribose/galactose/methyl galactoside import ATP-binding protein (HCH_01167) from Hahella chejuensis (strain KCTC 2396)

KEGG orthology group: K02056, simple sugar transport system ATP-binding protein [EC: 3.6.3.17] (inferred from 99% identity to spe:Spro_1962)

MetaCyc: 52% identical to D-galactose/methyl-galactoside ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-18-RXN; TRANS-RXN0-541

Predicted SEED Role

"Inositol transport system ATP-binding protein" in subsystem Inositol catabolism

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.17

Use Curated BLAST to search for 3.6.3.17

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (494 amino acids)

>IAI46_10095 sugar ABC transporter ATP-binding protein (Serratia liquefaciens MT49)
MYPYVLEAEGISKQFPGVKALDKVSIKIKPGSVHALMGENGAGKSTLMKCLIGIYHPDEG
TIKIKGQPVTFSDTLQALHSGISMIHQELNLVPYMTVAENIWLGREPAKLGFVNHDQLNK
KTRELLARLNIKLKPETLVGELSIASQQMVEIAKAVSYNADVLIMDEPTSALTEGEVVHL
FAIIRELREQGKGIIYISHKMDEIFAITDEVSIFRDGTFIASDKTENLTKQSLITMMVGR
ELTQMFPKFNNNIGEEVLRVEGLRRSDWFHDVSFSVKRGEILGVAGLVGAGRSEVMESLF
GMHPADGGSIFIEGKAAKVDSPSKAIELGLAFLTEDRKKSGLFLVLSVVENMSIVNLSEY
IGKNGFVSHVQMAKDCMEQIKKLNIKTPTMDQIINNLSGGNQQKVLIARWLLAQPKILIL
DEPTRGIDVGAKAEIYRLISELANRGVAIILVSSELPEILGMSDRVMVMHGGRITGILDK
EEADQEKILALASE