Protein Info for IAI46_09970 in Serratia liquefaciens MT49

Annotation: DUF533 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 217 transmembrane" amino acids 25 to 44 (20 residues), see Phobius details amino acids 55 to 74 (20 residues), see Phobius details PF04391: DUF533" amino acids 30 to 209 (180 residues), 170.3 bits, see alignment E=1.7e-54

Best Hits

Swiss-Prot: 56% identical to YEBE_ECOLI: Inner membrane protein YebE (yebE) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 99% identity to srr:SerAS9_1884)

Predicted SEED Role

"FIG004088: inner membrane protein YebE"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (217 amino acids)

>IAI46_09970 DUF533 domain-containing protein (Serratia liquefaciens MT49)
MKNNWMQQIQSMIGQKAGSIGGSEGIGKLLAPTALGGLVGVLLANKSSRKLVGKFGKNAL
IIGGSAAVGAVLWNKYKQRVKETHQNEPQFGLQTTPVDLRAKRLVQALVFAAKSDGHIDA
EEKLAIDHSLEQLQVGEEAQKWVQEAIDQPLNPDLIAQSVKNEDEALEVYYLSCMVIDVD
HFMERGYLDALAQSLKIPADVKQGIENDVNEKKRELA