Protein Info for IAI46_09265 in Serratia liquefaciens MT49

Annotation: kdo(2)-lipid A phosphoethanolamine 7''-transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 42 to 65 (24 residues), see Phobius details amino acids 72 to 96 (25 residues), see Phobius details amino acids 116 to 137 (22 residues), see Phobius details amino acids 157 to 174 (18 residues), see Phobius details PF08019: EptA_B_N" amino acids 55 to 188 (134 residues), 58.8 bits, see alignment E=6.2e-20 PF00884: Sulfatase" amino acids 245 to 533 (289 residues), 203.9 bits, see alignment E=3.7e-64

Best Hits

KEGG orthology group: None (inferred from 94% identity to spe:Spro_1859)

Predicted SEED Role

"Phosphoethanolamine transferase specific for the outer Kdo residue of lipopolysaccharide" in subsystem Lipid A modifications

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (550 amino acids)

>IAI46_09265 kdo(2)-lipid A phosphoethanolamine 7''-transferase (Serratia liquefaciens MT49)
MQKFRRWTQLQVSFFIAFYLGVLLNIPIFYRRYQQLHNDNLLSIGIEVVAAFCLVCFITL
LISFLGRRLFRVLATLLVLSSVAASYYMVLFHVDIGYGILAAVMTTDVDLSKESVGWHFG
IWMVLVSLLPLLFIWLAPMHEAAFKRGNQLALVKKGGIMLAAGLFCWLPLQLMGQVQDQH
DRENNQMMASYGGVVAGSYSPSNWLSALGLLTYSSYSQAEDSRNLFDPAAHFTYQPPKDV
NDLYVVFVIGESARRDHMGVYGYQRDNTPNLDKEANLAVLQGYSCDTSTKLSLRCMFVRE
GGASEEPQRTLKEMNVFSVLKKQGFSSELFSMQSEAWFYNKTQADSYALRESIQAEKRNA
GKPVDDIALIDELQDSLDRHPQGKHLVILHTKGSHYMYTERYPRAFARYQPECQGIDDTC
STESMINSYDNSLLYTDYVLEQVFNQLRNRNAIVFYASDHGESISENMHFHGTPRDHAPK
EQRTVPIMVWASDKFLSQPDHQAAFNQLKALQKAKTPVFHEKLFDSVLGCIGYTSPDGGI
VKQRNWCQVN