Protein Info for IAI46_09260 in Serratia liquefaciens MT49

Annotation: PTS cellobiose transporter subunit IIC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 453 transmembrane" amino acids 32 to 53 (22 residues), see Phobius details amino acids 73 to 95 (23 residues), see Phobius details amino acids 105 to 125 (21 residues), see Phobius details amino acids 145 to 167 (23 residues), see Phobius details amino acids 188 to 208 (21 residues), see Phobius details amino acids 218 to 267 (50 residues), see Phobius details amino acids 295 to 315 (21 residues), see Phobius details amino acids 327 to 346 (20 residues), see Phobius details amino acids 352 to 371 (20 residues), see Phobius details amino acids 379 to 397 (19 residues), see Phobius details amino acids 402 to 422 (21 residues), see Phobius details TIGR00359: PTS system, cellobiose-specific IIC component" amino acids 12 to 435 (424 residues), 490.9 bits, see alignment E=3.6e-151 TIGR00410: PTS system, lactose/cellobiose family IIC component" amino acids 12 to 435 (424 residues), 490.9 bits, see alignment E=3.6e-151 PF02378: PTS_EIIC" amino acids 29 to 360 (332 residues), 209.1 bits, see alignment E=4.4e-66

Best Hits

Swiss-Prot: 52% identical to PTJC_BACSU: Lichenan permease IIC component (licC) from Bacillus subtilis (strain 168)

KEGG orthology group: K02761, PTS system, cellobiose-specific IIC component (inferred from 97% identity to spe:Spro_1858)

Predicted SEED Role

"PTS system, cellobiose-specific IIC component (EC 2.7.1.69)" in subsystem Beta-Glucoside Metabolism (EC 2.7.1.69)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.69

Use Curated BLAST to search for 2.7.1.69

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (453 amino acids)

>IAI46_09260 PTS cellobiose transporter subunit IIC (Serratia liquefaciens MT49)
MAGLNSILERYVLPTALKIAGQKHILSVRDGIILNMPFMLIGSFFLIFAYLPIPSYANLM
GEVFGAAWRDKLLYPVKATYDIMAIISSFGIAYRLAEKYRGMDPLSTGAVSLVAFIMTIP
QHTLFAPVKGAAEQIVKGVLPMNFIGSQGLFVAIVVALLSTEIYRFVHNRNLVINMPEGV
PPAVAKSFLALIPGFCVLAVILVLRLIVEATPFGDINTMIATLIGIPMHHVGGTLPGMIF
SVILIGLLWTLGLHGDAIVLVFIQPVWLANMSENLVAFQNNQPIPHIITQQFYDLWIAPG
GTGALLGLVIFMLVRSRSAQMKQLGKIAAPGCLFNISEPMVFGIPLVMNPYFFLPFILTP
VVLVIVTYTAMATGLVTPPVGIALPFTTPIFISGYLATGGHISGTVIQVVNLLISMAIYY
PFFRAWDKQKYREENQAAASAPSAAVGEQPLTP