Protein Info for IAI46_09165 in Serratia liquefaciens MT49
Annotation: FAD-dependent oxidoreductase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 86% identity to spe:Spro_1841)MetaCyc: 58% identical to D-hydroxyproline dehydrogenase beta subunit (Pseudomonas aeruginosa PAO1)
1.14.19.-
Predicted SEED Role
"D-amino-acid oxidase (EC 1.4.3.3)" in subsystem Proline, 4-hydroxyproline uptake and utilization (EC 1.4.3.3)
MetaCyc Pathways
- superpathway of thiamine diphosphate biosynthesis II (10/11 steps found)
- trans-4-hydroxy-L-proline degradation II (4/4 steps found)
- thiazole component of thiamine diphosphate biosynthesis II (6/7 steps found)
- butanol and isobutanol biosynthesis (engineered) (4/8 steps found)
- L-lysine degradation V (4/9 steps found)
- superpathway of L-lysine degradation (13/43 steps found)
KEGG Metabolic Maps
- Arginine and proline metabolism
- D-Arginine and D-ornithine metabolism
- Glycine, serine and threonine metabolism
- Penicillin and cephalosporin biosynthesis
Isozymes
No predicted isozymesUse Curated BLAST to search for 1.4.3.3
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (374 amino acids)
>IAI46_09165 FAD-dependent oxidoreductase (Serratia liquefaciens MT49) MAADRRAEAIVVGAGIIGAACAWRLAQQGLQVLLVDNQRAGATAAGMGHLVCMDDNPAEL ALSAYSLQLWRSLVERLPENCAWRGCGTLWLAERDDEMAIAEAKCQRMAEYGVASEMQSA AQVAGLEPMLRPGLAGGLRVPGDGIVYAPNVARWLVNDVGSAIRVITGEACALEDRTIVL ASGERLTAPVVVLACGLQANRLLEQPMLRAKKGQLAITDRYPHRIHHQLVELGYGASAHA SGGTSVAFNVQARPTGQLLIGSSRQFDAPGNDIDFPLLAAMLARANAFLPTLAQMNVIRC WTGQRAASADGLPLLGPHPQHRWLWLALGHEGLGVTTALGSAELISAQIHHHRPAIDDTP YLAARMFSTEVLAI