Protein Info for IAI46_08915 in Serratia liquefaciens MT49

Annotation: CoA-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 137 PF13380: CoA_binding_2" amino acids 14 to 130 (117 residues), 144.2 bits, see alignment E=1.2e-46

Best Hits

Swiss-Prot: 71% identical to YCCU_ECOLI: Uncharacterized protein YccU (yccU) from Escherichia coli (strain K12)

KEGG orthology group: K06929, (no description) (inferred from 90% identity to spe:Spro_1762)

Predicted SEED Role

"Succinyl-CoA synthetase, alpha subunit-related enzymes"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (137 amino acids)

>IAI46_08915 CoA-binding protein (Serratia liquefaciens MT49)
MQDHEIADLLKQVKTIALVGASDNPSRPSFGVMAYLLSQGYQVTPVSPKLSGQTLLGQQA
YATLKDIPHPVDMVDVFRNSEAAYGVAQEAIAIGAKALWLQIGVINEQAEALAREAGLKV
VMDRCPKIELPRLGLER