Protein Info for IAI46_08890 in Serratia liquefaciens MT49

Annotation: TIGR01666 family membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 711 transmembrane" amino acids 18 to 37 (20 residues), see Phobius details amino acids 42 to 58 (17 residues), see Phobius details amino acids 66 to 85 (20 residues), see Phobius details amino acids 90 to 110 (21 residues), see Phobius details amino acids 117 to 137 (21 residues), see Phobius details amino acids 143 to 163 (21 residues), see Phobius details amino acids 390 to 409 (20 residues), see Phobius details amino acids 416 to 432 (17 residues), see Phobius details amino acids 439 to 460 (22 residues), see Phobius details amino acids 466 to 483 (18 residues), see Phobius details amino acids 489 to 507 (19 residues), see Phobius details amino acids 514 to 532 (19 residues), see Phobius details TIGR01666: TIGR01666 family membrane protein" amino acids 10 to 706 (697 residues), 1069.6 bits, see alignment E=0 TIGR01667: integral membrane protein, YccS/YhfK family" amino acids 10 to 706 (697 residues), 967.8 bits, see alignment E=3.1e-295 PF12805: FUSC-like" amino acids 68 to 347 (280 residues), 364.2 bits, see alignment E=6e-113 PF13515: FUSC_2" amino acids 405 to 526 (122 residues), 96 bits, see alignment E=2.8e-31

Best Hits

Swiss-Prot: 70% identical to YCCS_ECOLI: Inner membrane protein YccS (yccS) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 95% identity to spe:Spro_1757)

Predicted SEED Role

"Putative efflux (PET) family inner membrane protein YccS"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (711 amino acids)

>IAI46_08890 TIGR01666 family membrane protein (Serratia liquefaciens MT49)
MLSFAPAIRRYAYNSNLLYDLRIFIALAGAAAVPWWLGIPKLTIPLTLGVVAAALTDLDD
RLTGRLRNLLITLVCFFVASASIELLFPYPWLFALGLTTSTCGFILLGALGQRYATIAFG
ALLIAVYTMLGTSMYDAWYQQPMLLIIGALWYNLLTLIGHLIFPIRPLQENLARCYDQLA
NYLDAKANLFDPDAEQDADLPWMDVAMANSTLVTILNQTKASLLTRLKGDRGQRGTRRTL
HYYFVAQDIHERASSAHVQYQALSRQFRHSDILFRFQRLLSMQARACQQLAQSILMRQKY
QHNVRFEPAFARIDEALARVTLTPENRELTKALSHLLKNLRAIDAQLANIESEQALANGQ
VEENSLSDDRLTGWSDIRLRISRHLTPQSALFRHAIRMSVVLCIGYAFIQFTGMQHGYWI
LLTSLFVCQPNYNATRRRLALRIIGTLAGILVGLPILYFVPSVEGQLVLIVISGVLFFAF
RTVQYAHATMFITLLVLLCFNLLGEGFEVAAPRVYDTLLGCAIAWAAVSFIWPDWKFRQL
PTVVSKTLNANCRYLDAILVQYHQGKDNGLSYRIARRDAHNSDAELASVISNMSADPKAN
KDVQDAAFRLLCLNHTLLSYISALGAHRERLNNPATLDLLNDAVCYVDGALHQEEQDSGR
ITQALESLAERIQHAAPEPESKDQLVLQQIGLVIELLPELTMLNAQISKSA