Protein Info for IAI46_08580 in Serratia liquefaciens MT49

Annotation: dimethyl sulfoxide reductase subunit A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 817 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details TIGR02166: anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family" amino acids 14 to 817 (804 residues), 1334.5 bits, see alignment E=0 PF04879: Molybdop_Fe4S4" amino acids 59 to 117 (59 residues), 48.5 bits, see alignment 1e-16 PF00384: Molybdopterin" amino acids 120 to 574 (455 residues), 237.3 bits, see alignment E=3.9e-74 PF01568: Molydop_binding" amino acids 697 to 809 (113 residues), 92.6 bits, see alignment E=2.5e-30

Best Hits

Swiss-Prot: 81% identical to YNFE_ECOLI: Putative dimethyl sulfoxide reductase chain YnfE (ynfE) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 84% identity to eae:EAE_18385)

MetaCyc: 69% identical to putative selenate reductase YnfF (Escherichia coli K-12 substr. MG1655)
Selenate reductase. [EC: 1.97.1.9]

Predicted SEED Role

"Anaerobic selenate reductase, molybdenum cofactor-containing periplasmic protein"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.97.1.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (817 amino acids)

>IAI46_08580 dimethyl sulfoxide reductase subunit A (Serratia liquefaciens MT49)
MSENKENSQVSAGVSRRTLVKSGGIVGLAMAVGGIALPFSRRALADSISESVQKTAQDKV
VWGACSVNCGSRCALRLHVRDNEVYWVETDNTGLDAYGDHQVRACLRGRSIRRRMNHPDR
LNYPMKRVGKRGEGKFKRISWEEAFDSIADNLKRIVEQYGNEAVYINYTSGIVGGNITRS
SPNASLVARLMNCYGGYLSQYGTYSTAQIACAMPYTYGSNEGNSTSDIENSKLVVMFGNN
PAETRMSGGGITYYLEQARERSHARMIVIDPRYTDTAAGREDEWIPIRPGTDAALVAGLA
HVLISEQLVDQPFLDRYCIGYDEKTLPVDAPVNGHYKAYILGQGEDGVEKTPQWAAKITG
IPAERIIKLAREIGTAKPAYICQGWGPQRQANGELTSRAIAMLPILTGNVGINGGNSGAR
ESTYTITIERMPVLANPVKAQISCFSWTDAIVRGPEMTAKRDGVRGQDKLNVPIKFIWNY
AGNTITNQHSDINKTHDILQDESQCEMIVVLENFMTSSAKYADILLPDLMTVEQEDIIPN
DYAGNMGYLIFIQPATPAKFERKGIYEVLSEVARRLGPEVHQKFTEGRTQAQWLQHLYAK
MQDRDPLLPGYEELRSMGIYKRKDPNGHFVAYKKFRQDPEANPLKTPSGKIEIYSSRLAE
IADSWQLEKDETISPLPIYASTFEGWDDPLRNTYPLQMFGFHYKARTHSTYGNIDVLQAA
CRQEVWINPLDAQSRGIIGGDKVRVFNGRGEVRVEAKVTPRIMPGVVAMGQGAWHQADMR
GDRVDHGACMNTLTTHRPSPLAKGNPQHTNLIQIEKV