Protein Info for IAI46_08380 in Serratia liquefaciens MT49

Annotation: putrescine ABC transporter permease PotH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 319 transmembrane" amino acids 33 to 56 (24 residues), see Phobius details amino acids 104 to 125 (22 residues), see Phobius details amino acids 136 to 157 (22 residues), see Phobius details amino acids 187 to 209 (23 residues), see Phobius details amino acids 230 to 255 (26 residues), see Phobius details amino acids 286 to 307 (22 residues), see Phobius details PF00528: BPD_transp_1" amino acids 119 to 315 (197 residues), 74.6 bits, see alignment E=4.4e-25

Best Hits

Swiss-Prot: 83% identical to POTH_ECOLI: Putrescine transport system permease protein PotH (potH) from Escherichia coli (strain K12)

KEGG orthology group: K11075, putrescine transport system permease protein (inferred from 97% identity to spe:Spro_1647)

MetaCyc: 83% identical to putrescine ABC transporter membrane subunit PotH (Escherichia coli K-12 substr. MG1655)
ABC-25-RXN [EC: 7.6.2.11, 7.6.2.16]

Predicted SEED Role

"Putrescine transport system permease protein PotH (TC 3.A.1.11.2)" in subsystem Polyamine Metabolism (TC 3.A.1.11.2)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.6.2.11 or 7.6.2.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (319 amino acids)

>IAI46_08380 putrescine ABC transporter permease PotH (Serratia liquefaciens MT49)
MLAERTPPEPPANGPGPLKAFFQRLQMAHGRKLVIAVPLLWLTLLFLLPFLIVFKISLAE
LALAVPPYTDLMSWADGKLDIALNFANYLQLTDDPLYLDAYLQSLQVAAVSTVCCLIIGY
PLAWAVAHSKASTRNILLLLVILPSWTSFLIRVYAWMGILKNNGILNNFLLWLGVIDQPL
VILHTNLAVYIGVVYSYLPFMVLPIYTALTRLDYSLVEASLDLGAKPLKTFFSVIVPLTR
GGIIAGSMLVFIPAVGEFVIPELLGGPDSIMIGRVLWQEFFNNRDWPVASAVATVMLLLL
ILPIIWFHKHQNKEMGGQG