Protein Info for IAI46_08270 in Serratia liquefaciens MT49

Annotation: isopenicillin N synthase family oxygenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 339 PF14226: DIOX_N" amino acids 10 to 133 (124 residues), 114.7 bits, see alignment E=4e-37 PF03171: 2OG-FeII_Oxy" amino acids 183 to 279 (97 residues), 78 bits, see alignment E=6.2e-26

Best Hits

KEGG orthology group: K06892, (no description) (inferred from 92% identity to srs:SerAS12_1598)

Predicted SEED Role

"2-Oxobutyrate oxidase, putative" in subsystem Methionine Degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (339 amino acids)

>IAI46_08270 isopenicillin N synthase family oxygenase (Serratia liquefaciens MT49)
MTPPLTLKKLPLLDLSQLDGDAGQRQAFLDGLRIAARDVGFFYLRGHGVDSALNAQLQRL
ARQFFALPEADKLAVQMVHSPHFRGYNRAAAELTRGQPDWREQFDIGAERAALPLAEATP
RWARLQGPNQWPEALPELKPLLLQWQQTMTAMSLRLLRAFALSLSLPEQAFDSLYGDKPN
EHIKLIRYPGREATASGQGVGAHKDSGFLSFLLQDRQKGLQVEVDEGRWVDAEPLEDTFV
VNIGELLELATNGYLRATVHRVETPPAGSDRLSIAFFLGARLDAVVPVYQLPEYLAAEAH
GPTSDPHNPLLRDVGFNYLKGRIRSHPDVAQRYYQDVVA