Protein Info for IAI46_07975 in Serratia liquefaciens MT49

Annotation: uridine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

Best Hits

Swiss-Prot: 99% identical to URK_SERP5: Uridine kinase (udk) from Serratia proteamaculans (strain 568)

KEGG orthology group: K00876, uridine kinase [EC: 2.7.1.48] (inferred from 99% identity to spe:Spro_1576)

MetaCyc: 90% identical to uridine/cytidine kinase (Escherichia coli K-12 substr. MG1655)
Uridine kinase. [EC: 2.7.1.213, 2.7.1.48]; 2.7.1.48 [EC: 2.7.1.213, 2.7.1.48]; 2.7.1.48 [EC: 2.7.1.213, 2.7.1.48]; 2.7.1.48 [EC: 2.7.1.213, 2.7.1.48]

Predicted SEED Role

"Uridine kinase (EC 2.7.1.48) [C1]" (EC 2.7.1.48)

MetaCyc Pathways

superpathway of pyrimidine ribonucleosides salvage (10/10 steps found)
pyrimidine ribonucleosides salvage I (3/3 steps found)
nucleoside and nucleotide degradation (archaea) (4/10 steps found)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.213 or 2.7.1.48

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (213 amino acids)

>IAI46_07975 uridine kinase (Serratia liquefaciens MT49)
MTDKPHQCVIIGIAGASASGKSLIASTLYRELRDQVGDEHIGVIPEDSYYKDQTHLTMEE
RVKTNYDHPSAMDHNLLFQHLQMLKSGRAIELPLYSYTEHTRKKETVHLEPKKVIILEGI
LLLTDIRLRQEMNFSIFVDTPLDICLMRRMKRDVNERGRSMDSVMAQYQKTVRPMFLQFI
EPSKQYADIIVPRGGKNRIAIDILKAKISQFFE