Protein Info for IAI46_07925 in Serratia liquefaciens MT49

Annotation: galactose/methyl galactoside ABC transporter permease MglC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 336 transmembrane" amino acids 13 to 37 (25 residues), see Phobius details amino acids 45 to 66 (22 residues), see Phobius details amino acids 72 to 91 (20 residues), see Phobius details amino acids 103 to 130 (28 residues), see Phobius details amino acids 132 to 153 (22 residues), see Phobius details amino acids 183 to 201 (19 residues), see Phobius details amino acids 228 to 248 (21 residues), see Phobius details amino acids 268 to 299 (32 residues), see Phobius details amino acids 311 to 330 (20 residues), see Phobius details PF02653: BPD_transp_2" amino acids 41 to 325 (285 residues), 163.8 bits, see alignment E=2.3e-52

Best Hits

Swiss-Prot: 89% identical to MGLC_ECOLI: Galactoside transport system permease protein MglC (mglC) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to srr:SerAS9_1534)

MetaCyc: 89% identical to D-galactose/methyl-galactoside ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
ABC-18-RXN; TRANS-RXN0-541

Predicted SEED Role

"Galactose/methyl galactoside ABC transport system, permease protein MglC (TC 3.A.1.2.3)" in subsystem Lactose and Galactose Uptake and Utilization (TC 3.A.1.2.3)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (336 amino acids)

>IAI46_07925 galactose/methyl galactoside ABC transporter permease MglC (Serratia liquefaciens MT49)
MNALNKKTLFTYFKEGGIYVVLLVLLAIIIIQDPTFLSLMNLSNILTQSSVRIIIALGVA
GLIVTQGTDLSAGRQVGLAAVIAATLLQSMDNVNKVFPHMETWSIPLVILLVCAVGAVIG
LVNGLIIAYLNVTPFITTLGTMIIVYGINSLYYDSVGASPVAGFDPKFSTFAQGFLRFGD
FKLSYITFYAIIAIIFVWILWNKTRFGKNIFAIGGNPEAAKVSGVNVPLNLIMIYALSGV
FYAFGGLLEAGRIGSATNNLGFMYELDAIAACVVGGVSFAGGVGTVLGVVTGVIIFTVIN
YGLTYIGVNPYWQYIIKGGIIIFAVALDSLKYAKKK