Protein Info for IAI46_07785 in Serratia liquefaciens MT49

Annotation: winged helix-turn-helix transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 227 transmembrane" amino acids 182 to 199 (18 residues), see Phobius details PF01022: HTH_5" amino acids 19 to 64 (46 residues), 33.6 bits, see alignment 2.8e-12

Best Hits

KEGG orthology group: None (inferred from 88% identity to srr:SerAS9_1501)

Predicted SEED Role

"Transcriptional regulator, ArsR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (227 amino acids)

>IAI46_07785 winged helix-turn-helix transcriptional regulator (Serratia liquefaciens MT49)
MNNIDIEDRLAALSGAIADRTRARMLCLLMDGRAYTATELSAAVDVAASTASGHLARLQE
QRLIACVKQGRYRYFRLAGPEVAAALETLMALAGVEKPVVKSTTPTSLQFARTCYDHLAG
EVAVKLHQRLHQLTWLEGEEDYRLSEAGHAALTRLGVDCSPAPSRRRFACGCLDWSERKA
HLGGALGAAMLTAFIRRGWIKRQLESRELQLTASGKKALKAHFDLTV