Protein Info for IAI46_07725 in Serratia liquefaciens MT49

Annotation: FMN-binding glutamate synthase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 540 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 33 to 50 (18 residues), see Phobius details PF01645: Glu_synthase" amino acids 159 to 475 (317 residues), 281 bits, see alignment E=8.2e-88

Best Hits

KEGG orthology group: None (inferred from 96% identity to spe:Spro_1516)

Predicted SEED Role

"Ferredoxin-dependent glutamate synthase (EC 1.4.7.1)" in subsystem Ammonia assimilation or Glutamine, Glutamate, Aspartate and Asparagine Biosynthesis (EC 1.4.7.1)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.4.7.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (540 amino acids)

>IAI46_07725 FMN-binding glutamate synthase family protein (Serratia liquefaciens MT49)
MKSSLFSRYTCLVLSLLLTLASLALLSHSPWFWLPTIIFGGLSALGIYDLTQQRHAICRN
YPIIGRLRFFFEFIRPEIRQYLLEEDNAQIPFSRTQRTLVYRRAKNEMGDKPFGTQLDVY
QTGYECIGHSMRPVEVSDPTSFRVTIGGPDCSQPYSASIFNISAMSFGALSANAIRALNL
GAAKGNFYHDTGEGSISRYHRENGGDLVWELGSGYFGCRTADGHFDPQRFTEQAKKPQVR
MIEIKLSQGAKPGHGGILPAKKVDAEIAATRGVPEGVDCISPASHSAFSTPIEMMHFIQQ
LRELSGGKPVGFKLCIGHPWEFVAIAKAMLQTQILPDFIVVDGKEGGTGAAPLELSNYMG
MPLREGLLFVHNTLVGCGLRDKIKIGASGKIISAFDIASVLVLGADWVNSARGFMFAVGC
IQSQSCHTNHCPTGVATQDPLRQKALVVPNKAERVYHFHQNTVKALAEMLAAAGVSRPEQ
LTSHHMLRRITSTEIKVYADIYYYLEPGALLQKEIESDFYARMWRMATPNSFDQAIALPA