Protein Info for IAI46_07595 in Serratia liquefaciens MT49

Annotation: aldolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00596: Aldolase_II
  • amino acids 11 to 188 (178 residues), 164.3 bits, E=1.5e-52

Best Hits

Swiss-Prot: 81% identical to OTNC_PECAS: 3-oxo-tetronate 4-phosphate decarboxylase (otnC) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: None (inferred from 97% identity to spe:Spro_1490)

MetaCyc: 62% identical to 3-dehydro-4-phosphotetronate decarboxylase (Haemophilus influenzae Rd KW20)
RXN-18589 [EC: 1.1.1.409, 4.1.1.104]; RXN-18588 [EC: 1.1.1.409, 4.1.1.104, 1.1.1.408]

Predicted SEED Role

"Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases"

MetaCyc Pathways

• L-threonate degradation (3/4 steps found)
• D-erythronate degradation II (2/4 steps found)
• D-erythronate degradation I (1/3 steps found)
• D-threonate degradation (1/3 steps found)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.1.408 or 1.1.1.409 or 4.1.1.104

Protein Sequence (210 amino acids)

>IAI46_07595 aldolase (Serratia liquefaciens MT49)
MTMTTEQQAREEMVRLGASFFQRGYATGSAGNLSLLLADGTLLATPTGSCLGELQAERLS
KVSLNGEWLSGDKPSKEISFHRALYLNNPECKAVVHLHCTYLTALSCLQGLDVENAIKPF
TPYVVMRVGKVPVVPYYRPGDLRLAEDLAKLAPTHRAFLLANHGPVVTGKDLRAAADNTE
EMEDAARLIFTLGDRPIRYLTDDEITELRS