Protein Info for IAI46_07520 in Serratia liquefaciens MT49

Annotation: mechanosensitive channel protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 739 signal peptide" amino acids 1 to 36 (36 residues), see Phobius details transmembrane" amino acids 136 to 157 (22 residues), see Phobius details amino acids 185 to 207 (23 residues), see Phobius details amino acids 226 to 246 (21 residues), see Phobius details amino acids 270 to 289 (20 residues), see Phobius details amino acids 296 to 317 (22 residues), see Phobius details amino acids 337 to 363 (27 residues), see Phobius details amino acids 374 to 396 (23 residues), see Phobius details amino acids 429 to 450 (22 residues), see Phobius details amino acids 468 to 490 (23 residues), see Phobius details amino acids 511 to 532 (22 residues), see Phobius details amino acids 539 to 559 (21 residues), see Phobius details PF21088: MS_channel_1st" amino acids 517 to 558 (42 residues), 37.4 bits, see alignment 3e-13 PF00924: MS_channel_2nd" amino acids 559 to 623 (65 residues), 55.1 bits, see alignment E=9.7e-19 PF21082: MS_channel_3rd" amino acids 633 to 717 (85 residues), 29.8 bits, see alignment E=9.9e-11

Best Hits

Swiss-Prot: 49% identical to YBIO_ECOLI: Moderate conductance mechanosensitive channel YbiO (ybiO) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 88% identity to spe:Spro_1476)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (739 amino acids)

>IAI46_07520 mechanosensitive channel protein (Serratia liquefaciens MT49)
MPATAYSRFGSHLREQLFPLLLLLITYAVSPLATAQPAQDPAPSGQTEQQKASYAALADI
LQDDKARAELINHLRQAADQPAAAQPKSATPEPSDSLSESLTSLAQDSLSTLDKKLNSRQ
KLIDSGPKRTFHPDVFFRALGYFLLTVALTFALFHLIRRIIRPLYKRIGNWGHNAKLQHD
SWYKLPTAILGAFAIDLLVLLLALTAGNLFARHVHADNATILRLQTLFLSAFAVIEFFKA
VLRLIFAPNFDYLRPFAFSDAVAHYWNTRLAWLSGLIGYGLMVVVPVVATQISYPAAAAA
NLVIMLALTLYALALILRNRKPIQLQINLLAERSMAFFSIILRGLGHVWHLLAIAYFLVL
FVLSQFDIGNSLNFMMTATVKSLVVIGVGALISGQLTRWIFRRISLPDDVNRRYPMLERR
INSYIPNGLKILRVMVVLTVTLLLFDAWHLINLYQWASSENGEKIVGGLVHILLILVIAV
ISWTLMASVIEHRLALELSNGIRPSARERTLLTLFRNVLAIVISTITIMIVLSQVGINIA
PLLAGAGALGLAISFGAQTLVKDVITGVFIQFENGMNTGEYVTVSGITGTVERMTIRSIG
LRDDYGVYHIVPFSSITTLANYAREFGVYRANYSVSRDEDIDHVHEVLHQAVAALKQDEQ
VKSFLVGEPVFNGVVALGDRSFTTRVTVRTQALKQWVVQYALDRLVKIHFDQAGIAMPQQ
AMQLSYAPGTQQSATKQVE