Protein Info for IAI46_07205 in Serratia liquefaciens MT49

Annotation: sigma-54-dependent Fis family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 628 PF14532: Sigma54_activ_2" amino acids 13 to 177 (165 residues), 69.4 bits, see alignment E=9.8e-23 PF00158: Sigma54_activat" amino acids 16 to 172 (157 residues), 228.8 bits, see alignment E=8.1e-72 PF07728: AAA_5" amino acids 30 to 147 (118 residues), 31.8 bits, see alignment E=3.4e-11 PF02954: HTH_8" amino acids 289 to 314 (26 residues), 23.5 bits, see alignment (E = 9.7e-09) TIGR01728: ABC transporter, substrate-binding protein, aliphatic sulfonates family" amino acids 347 to 627 (281 residues), 169.8 bits, see alignment E=3.8e-54 PF09084: NMT1" amino acids 388 to 566 (179 residues), 35.9 bits, see alignment E=1.9e-12

Best Hits

KEGG orthology group: None (inferred from 87% identity to ebi:EbC_20690)

Predicted SEED Role

"Alkanesulfonates-binding protein" in subsystem Alkanesulfonate assimilation or Alkanesulfonates Utilization or Putative sulfate assimilation cluster

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (628 amino acids)

>IAI46_07205 sigma-54-dependent Fis family transcriptional regulator (Serratia liquefaciens MT49)
MQSSGPRLIDPASLAFQNVLDRLAPTDATVLIVGETGTGKELMARYLHHHSLRRDRPFLA
VNCGALTESLAESELFGHEKGAFTGAVDRHQGWFEAAEGGTLLLDEIGELSLPLQVKLLR
VLQEREVTRVGSHRPVKVNVRVVAATHVDLANAIRERRFREDLYYRLNVAAVTLPPLRQR
RQDIPLLAEHFLTLYARRLGRPQLRLSAEALATLMDYPWPGNIRELENTLHNAVLLSKAP
LITPQQLRLSAEMASLPPQGDASLDSFLRQQLVGNDGPLYQRVIDSLVRNAFELSQGNQL
QAAALLGISRNTLRTHLGHLGLIKARRSVGGTALKSGRRTGSRERELRIGYQKFGNLGIL
KARQSLEARLVDSGVSVLWSEFPAGPQLLHALTNREIDFGTTGEVPPLFAQAGNSPLLYV
AWEPAAPQSVALLVTDDSPIRTLADLRGKRIAVNKGSNVHYLLLQILDEAGLTLEDVRVV
YAPPKYPLTPSDHHAVDAWMMWDPLLSDAEQSGQFRVIANGVGRVSNHQFYLAHRDFAGH
SSDLLHGLMAALEQTGRYIDAHRDEAATLLSAELGQGIPSLTHALARRSHQTRRMDLNII
RQQQAIADRFYALGLLPRAIKVREAIWQ