Protein Info for IAI46_06630 in Serratia liquefaciens MT49

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 534 transmembrane" amino acids 14 to 34 (21 residues), see Phobius details amino acids 63 to 80 (18 residues), see Phobius details amino acids 87 to 105 (19 residues), see Phobius details amino acids 111 to 134 (24 residues), see Phobius details amino acids 144 to 165 (22 residues), see Phobius details amino acids 174 to 196 (23 residues), see Phobius details amino acids 208 to 228 (21 residues), see Phobius details amino acids 240 to 261 (22 residues), see Phobius details amino acids 281 to 301 (21 residues), see Phobius details amino acids 313 to 337 (25 residues), see Phobius details amino acids 344 to 362 (19 residues), see Phobius details amino acids 374 to 399 (26 residues), see Phobius details amino acids 496 to 515 (20 residues), see Phobius details PF07690: MFS_1" amino acids 26 to 421 (396 residues), 93 bits, see alignment E=8.9e-31

Best Hits

KEGG orthology group: None (inferred from 89% identity to spe:Spro_1333)

Predicted SEED Role

"Inner membrane component of tripartite multidrug resistance system" in subsystem Multidrug Resistance, Tripartite Systems Found in Gram Negative Bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (534 amino acids)

>IAI46_06630 MFS transporter (Serratia liquefaciens MT49)
MNVQPAPAAAPHPFTLRLALGLVGVLIAALTSGLNDRLSDLALADIRAAIGIGYDEASWI
TSSYQAAEVAAMMVAPWFAVTFSLRRFALVMVSGFAAVGVLQPLISDPTLFIALRIVQGL
FGGALPPLLMTVALRFLPPGIKLYGLAAYALTATFGPNVAAPLAALWTDHLGWQFVFWQA
IPLCFIASLLMGWGLPQDPLRLERLHQIDLFGMLTGCSGIALLILSLTQGERLDWFNSPL
ISLMLPVSIALLVTFLINEWYHPLPLFKLQMLKRINLSHSLLTLAGVLILGLSGSLLPSF
YFSQVEGFRTAQFAPLALTIGLPQLVIAPLVATLLNFRWIDCRWMLAAGAGLIVSACLLG
MQLTDDWARQNFWLIQSLLAFGQPMMILPVLMTSTSVVLAPEGPFASAMFNTVRGFSTVA
AGSLVENFMSHREKFHSQVLVDRLGNSPWLMTAENSEQASGDMPLLPDGSISSAENLGHF
STLVKHQAMILSISDAYLLIICCALLLVLLTAWLPTRVYPPQTLLPLVPKTSGS